L-threo-PPMP, Glucosylceramide synthase inhibitor (ab144105)

Overview

  • Product name

    L-threo-PPMP, Glucosylceramide synthase inhibitor
  • Description

    Glucosylceramide synthase inhibitor
  • Biological description

    Glucosylceramide synthase inhibitor. Induces apoptosis via caspase-3 activation. Anticancer agent. Active in vitro.

    See similar compounds
  • Purity

    > 98%
  • CAS Number

    207278-87-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Basu S  et al. Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP. Glycoconj J 20:157-68 (2004). Read more (PubMed: 15090729) »
  • Bleicher RJ & Cabot MC Glucosylceramide synthase and apoptosis. Biochim Biophys Acta 1585:172-8 (2002). Read more (PubMed: 12531551) »

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