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We require anti-L1 CAM antibody that detects full length as well as all its cleaved products in mouse brain. I have come across one of your product anti-L1CAM antibody [2C2] - Neuronal Marker (ab24345) that shows 200 kD, 80 kD and 60 kD bands. In addition, it is mentioned that it may detect other cleaved products theoretically. However, before ordering the antibody we want to be sure that it also detects all the bands (full length of 220, 200kD as well as 180, 140, 80 and 40 kD).
Is there is any possibility to provide a very small aliqout of the same (may be 2-5 microlitre) to check whether it serves our interest. Alternatively, if you are sure for what is mentioned in the catalogue, we may order it on approval basis.
Asked on Dec 27 2012
Thank you for your interest in this antibody. Two customers sent their mouse western blot results, both showing detection of bands that they assumed represented the full-length protein and a fragment. However, we do not guarantee that the antibody will detect all possible fragments, and we do not offer free samples. Here are links to the two reviews.
Given these results, it seems unlikely that the antibody will be sensitive enough to detect all fragments, assuming the fragments (220, 200, 180, 140, 80 and 40 kDa) are present in these samples.
Answered on Dec 27 2012