Product nameAnti-L3MBTL2 antibody
See all L3MBTL2 primary antibodies
DescriptionRabbit polyclonal to L3MBTL2
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse, Cow, Orangutan
Recombinant fragment corresponding to Human L3MBTL2 aa 1-230.
MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEE SSEAENEDREAGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTRE AFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSA KIGAFLHSQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKH VPLYDQWEDVMKGMKVEVLNSDAVLPSRVY
Database link: Q969R5
- WB: K562 whole cell lysate; Rat heart tissue lysate. ICC/IF: HeLa cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.03% Proclin
Constituents: 50% Glycerol, PBS
Concentration information loading...
PurityProtein G purified
Purification notesPurity greater than 95%.
Our Abpromise guarantee covers the use of ab237628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/2000. Predicted molecular weight: 79 kDa.|
|ICC/IF||1/50 - 1/200.|
FunctionPutative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Sequence similaritiesContains 1 FCS-type zinc finger.
Contains 4 MBT repeats.
- Information by UniProt
- 3bt like 2 protein antibody
- 3bt like protein antibody
- DKFZP761I141 antibody
All lanes : Anti-L3MBTL2 antibody (ab237628) at 1/200 dilution
Lane 1 : K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate
Lane 2 : Rat heart tissue lysate
All lanes : Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 79 kDa
HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for L3MBTL2 (green) using ab237628 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody.
ab237628 has not yet been referenced specifically in any publications.