Overview

  • Product name

    Anti-Lactate Dehydrogenase antibody
    See all Lactate Dehydrogenase primary antibodies
  • Description

    Rabbit polyclonal to Lactate Dehydrogenase
  • Host species

    Rabbit
  • Specificity

    This antibody will cross-react with LDHA, LDHB and LDHC.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Lactate Dehydrogenase aa 230-270 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. The immunogen range is within aa 230-270.
    Sequence:

    I HKQVIQSAYE IIKLKGYTSW AIGLSVMDLV GSILKNLRRV


    Database link: P07864

  • Positive control

    • Rat testis and human rectal carcinoma tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab203285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 36 kDa.
IHC-P 1/100 - 1/500.

When using a fluorescent probe please use a dilution range of 1/50 - 1/200.

Target

  • Pathway

    Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.
  • Involvement in disease

    Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
  • Sequence similarities

    Belongs to the LDH/MDH superfamily. LDH family.
  • Post-translational
    modifications

    ISGylated.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cell proliferation-inducing gene 19 protein antibody
    • GSD11 antibody
    • L lactate dehydrogenase B chain antibody
    • L-lactate dehydrogenase A chain antibody
    • Lactate dehydrogenase A antibody
    • Lactate dehydrogenase B antibody
    • Lactate dehydrogenase c variant 1 antibody
    • Lactate dehydrogenase c variant 3 antibody
    • Lactate dehydrogenase c variant 4 antibody
    • Lactate dehydrogenase C4 antibody
    • Lactate dehydrogenase H chain antibody
    • Lactate dehydrogenase M antibody
    • LDH A antibody
    • LDH B antibody
    • LDH H antibody
    • LDH heart subunit antibody
    • LDH M antibody
    • LDH muscle subunit antibody
    • LDH-A antibody
    • LDH-M antibody
    • LDH1 antibody
    • ldha antibody
    • LDHA_HUMAN antibody
    • LDHBD antibody
    • LDHM antibody
    • MS1111 antibody
    • PIG19 antibody
    • Proliferation inducing gene 19 antibody
    • Proliferation-inducing gene 19 antibody
    • Renal carcinoma antigen NY REN 46 antibody
    • Renal carcinoma antigen NY-REN-59 antibody
    • TRG 5 antibody
    • TRG5 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded human rectal carcinoma tissue labeling Lactate Dehydrogenase C using ab203285 at 1/200, followed by secondary detection and DAB staining.

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded rat testis tissue labeling Lactate Dehydrogenase C using ab203285 at 1/200, followed by secondary detection and DAB staining.

References

ab203285 has not yet been referenced specifically in any publications.

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