Overview

  • Product name
    Lactofen, Herbicidal and tumorigenic agent
  • Description
    Herbicidal and tumorigenic agent
  • Biological description
    Herbicidal and tumorigenic agent. Protoporphyrinogen oxidase inhibitor. Induces singlet oxygen generation and cell death. Induces necrosis. Induces late expression of PR-1a, PR-5, and PR-10 in proximal tissues. Shows tumorigenic effects in vivo. Orally active.
  • Purity
    > 99%
  • CAS Number
    77501-63-4
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Patzoldt WL  et al. A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidase. Proc Natl Acad Sci U S A 103:12329-34 (2006). Read more (PubMed: 16894159) »
  • Graham MY The diphenylether herbicide lactofen induces cell death and expression of defense-related genes in soybean. Plant Physiol 139:1784-94 (2005). Read more (PubMed: 16299178) »
  • Butler EG  et al. Induction of hepatic peroxisome proliferation in mice by lactofen, a diphenyl ether herbicide. Toxicol Appl Pharmacol 93:72-80 (1988). Read more (PubMed: 3354002) »

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