Overview

  • Product name

    Anti-LAG-3 antibody [17B4] - BSA and Azide free
    See all LAG-3 primary antibodies
  • Description

    Mouse monoclonal [17B4] to LAG-3 - BSA and Azide free
  • Host species

    Mouse
  • Tested applications

    Suitable for: ICC/IF, WB, IP, IHC-Fr, Inhibition Assaymore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human LAG-3 aa 70-99. First N-terminal D1 domain.
    Sequence:

    GPPAAAPGHPLAPGPHPAAPSSWGPRPRRY


    Database link: P18627-1

  • Epitope

    Recognizes the 30 aa extra-loop of the first N-terminal D1 domain of LAG-3.
  • General notes

    Endotoxin level: 0.03 EU/mg of protein.

    This product was previously labelled as Lymphocyte Activation Gene 3.

Properties

Applications

Our Abpromise guarantee covers the use of ab237013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 58 kDa.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
Inhibition Assay Use at an assay dependent concentration.

Target

  • Function

    Involved in lymphocyte activation. Binds to HLA class-II antigens.
  • Tissue specificity

    On cell surface of activated NK and T-lymphocytes.
  • Sequence similarities

    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD223 antibody
    • CD223 antigen antibody
    • FDC protein antibody
    • LAG-3 antibody
    • Lag3 antibody
    • LAG3_HUMAN antibody
    • Lymphocyte activating 3 antibody
    • Lymphocyte activation gene 3 antibody
    • Lymphocyte activation gene 3 protein antibody
    • Protein FDC antibody
    see all

References

ab237013 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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