Key features and details
- Sheep polyclonal to Laminin alpha 4/LAMA4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Laminin alpha 4/LAMA4 antibody
See all Laminin alpha 4/LAMA4 primary antibodies
DescriptionSheep polyclonal to Laminin alpha 4/LAMA4
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant fragment corresponding to Human Laminin alpha 4/LAMA4 aa 826-1816. (Derived from Chinese hamster ovary cell line CHO).
RSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELT ETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVS SWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDL DPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIY NMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRF DIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDT LKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYI GGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGY GCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYY ASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYE LIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAY FTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKAS QNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGT ANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLA HGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVL EESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNG ASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFE VRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQS LCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVP ESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVS
Database link: Q16363
- Human placenta tissue lysate.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituent: 100% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe IgG fraction of immunized serum was purified by antigen affinity chromatography.
Our Abpromise guarantee covers the use of ab214935 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/2000. Detects a band of approximately 210 kDa (predicted molecular weight: 202 kDa).|
FunctionBinding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Tissue specificityIn adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis.
Involvement in diseaseCardiomyopathy, dilated 1JJ
Sequence similaritiesContains 4 laminin EGF-like domains.
Contains 5 laminin G-like domains.
DomainThe alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
Domain G is globular.
Cellular localizationSecreted, extracellular space, extracellular matrix, basement membrane. Major component.
- Information by UniProt
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Anti-Laminin alpha 4/LAMA4 antibody (ab214935) at 1/1000 dilution + Human placenta tissue lysate
Predicted band size: 202 kDa
Observed band size: 210 kDa why is the actual band size different from the predicted?
ab214935 has not yet been referenced specifically in any publications.