Overview

  • Product name

    Anti-Laminin alpha 5/LAMA5 antibody
    See all Laminin alpha 5/LAMA5 primary antibodies
  • Description

    Rabbit polyclonal to Laminin alpha 5/LAMA5
  • Host species

    Rabbit
  • Specificity

    ab75344 reacts specifically withLaminin alpha 5/LAMA5 protein.

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Mouse Laminin alpha 5/LAMA5 (C terminal).
    (Peptide available as ab206774)

  • General notes

     This product was previously labelled as Laminin alpha 5

     

Properties

Applications

Our Abpromise guarantee covers the use of ab75344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 404 kDa.Can be blocked with Laminin alpha 5/LAMA5 peptide (ab206774).

Target

  • Function

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
  • Tissue specificity

    Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.
  • Sequence similarities

    Contains 22 laminin EGF-like domains.
    Contains 5 laminin G-like domains.
    Contains 1 laminin IV type A domain.
    Contains 1 laminin N-terminal domain.
  • Domain

    Domain G is globular and is part of the major cell-binding site located in the long arm of the laminin heterotrimer.
  • Cellular localization

    Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
  • Information by UniProt
  • Database links

  • Alternative names

    • KIAA0533 antibody
    • KIAA1907 antibody
    • LAMA5 antibody
    • LAMA5_HUMAN antibody
    • Laminin alpha 5 chain antibody
    • Laminin subunit alpha 5 antibody
    • Laminin subunit alpha-5 antibody
    • Laminin, alpha 5 antibody
    • Laminin-10 subunit alpha antibody
    • Laminin-11 subunit alpha antibody
    • Laminin-15 subunit alpha antibody
    • RP11-157P1.6 antibody
    see all

References

This product has been referenced in:

  • Blanco S  et al. Stem cell function and stress response are controlled by protein synthesis. Nature 534:335-40 (2016). IHC ; Mouse . Read more (PubMed: 27306184) »
See 1 Publication for this product

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