Lamivudine, nucleoside analog reverse transcriptase inhibitor (ab143062)

Overview

  • Product name

    Lamivudine, nucleoside analog reverse transcriptase inhibitor
  • Description

    Potent nucleoside analog reverse transcriptase inhibitor
  • Biological description

    Potent nucleoside analog reverse transcriptase inhibitor (IC50 = 2 μM). Inhibits both HIV1 and HIV2 reverse transcriptase. Orally active. Anti-HIV agent. Active in vivo and in vitro.
  • Purity

    > 99%
  • CAS Number

    134678-17-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Perez-Olmeda M  et al. In vitro analysis of synergism and antagonism of different nucleoside/nucleotide analogue combinations on the inhibition of human immunodeficiency virus type 1 replication. J Med Virol 81:211-6 (2009). Read more (PubMed: 19107982) »
  • Ravetti S  et al. Synthesis and anti-HIV activity of novel 2',3'-dideoxy-3'-thiacytidine prodrugs. Bioorg Med Chem 17:6407-13 (2009). Read more (PubMed: 19660957) »
  • Bayram S & Topaktas M Confirmation of the chromosome damaging effects of lamivudine in in vitro human peripheral blood lymphocytes. Environ Mol Mutagen 49:328-33 (2008). Read more (PubMed: 18366100) »

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