Product nameAnti-LAMTOR1 antibody
See all LAMTOR1 primary antibodies
DescriptionRabbit polyclonal to LAMTOR1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Rhesus monkey
- WB: HeLa and SK-N-SH whole cell extracts.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin
Constituents: PBS, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab229760 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 18 kDa.|
FunctionRegulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.
Sequence similaritiesBelongs to the LAMTOR1 family.
Cellular localizationLate endosome membrane. Lysosome membrane. Cell membrane.
- Information by UniProt
- C11orf59 antibody
- LAMTOR1 antibody
- Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 antibody
All lanes : Anti-LAMTOR1 antibody (ab229760) at 1/1000 dilution
Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell extract
Lane 2 : SK-N-SH (human neuroblastoma cell line) whole cell extract
Lysates/proteins at 60 µg per lane.
All lanes : HRP-conjugated anti-rabbit IgG
Predicted band size: 18 kDa
15% SDS-PAGE gel.
ab229760 has not yet been referenced specifically in any publications.