Overview

  • Product name
    Anti-LAMTOR1 antibody - N-terminal
    See all LAMTOR1 primary antibodies
  • Description
    Rabbit polyclonal to LAMTOR1 - N-terminal
  • Host species
    Rabbit
  • Specificity
    ab181017 is predicted to not cross-react with other LAMTOR family proteins.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human LAMTOR1 (N terminal). 17 amino acid peptide.
    Database link: Q6IAA8

  • Positive control
    • A431 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab181017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 18 kDa.

Target

  • Function
    Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation.
  • Sequence similarities
    Belongs to the LAMTOR1 family.
  • Cellular localization
    Late endosome membrane. Lysosome membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C11orf59 antibody
    • LAMTOR1 antibody
    • Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1 antibody
    • Lipid raft adaptor protein p18 antibody
    • LTOR1_HUMAN antibody
    • p18 antibody
    • p27Kip1-releasing factor from RhoA antibody
    • p27RF-Rho antibody
    • PDRO antibody
    • PP7157 antibody
    • Protein associated with DRMs and endosomes antibody
    • Ragulator complex protein LAMTOR1 antibody
    • ragulator complex protein PDRO antibody
    • Ragulator1 antibody
    • RhoA activator C11orf59 antibody
    see all

Images

  • Anti-LAMTOR1 antibody - N-terminal (ab181017) at 1 µg/ml + A431 cell lysate at 15 µg

    Predicted band size: 18 kDa

References

ab181017 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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