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    lano-antibody-ab127568.pdf

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Epigenetics and Nuclear Signaling Transcription Domain Families Developmental Families Other
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Anti-Lano antibody (ab127568)

  • Datasheet
  • SDS
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Western blot - Anti-Lano antibody (ab127568)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lano antibody (ab127568)

Key features and details

  • Rabbit polyclonal to Lano
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-Lano antibody
  • Description

    Rabbit polyclonal to Lano
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein fragment corresponding to a region within amino acids 265 and 497 of Human Lano (UniProt Q9BTT6).

  • Positive control

    • A549, HeLa andcell lysates HepG2, HCT116 cell lysate; Human breast carcinoma tissue
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Epigenetics and Nuclear Signaling
    • Transcription
    • Domain Families
    • Developmental Families
    • Other

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Positive Controls

    • Hep G2 cytoplasmic extract lysate (ab14659)
    • HeLa membrane extract lysate (ab29547)
    • A549 whole cell lysate (ab7910)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab127568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/500 - 1/3000. Predicted molecular weight: 59 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Notes
WB
1/500 - 1/3000. Predicted molecular weight: 59 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificity

    Expressed strongly in testis and placenta, followed by heart, lung, kidney, thyroid, trachea, colon, prostate and pancreas.
  • Sequence similarities

    Contains 17 LRR (leucine-rich) repeats.
  • Cellular localization

    Cytoplasm. Membrane. Localized at the basolateral side of epithelial cells.
  • Target information above from: UniProt accession Q9BTT6 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 55227 Human
    • Entrez Gene: 214345 Mouse
    • Omim: 608195 Human
    • SwissProt: Q9BTT6 Human
    • SwissProt: Q80VQ1 Mouse
    • Unigene: 646997 Human
    • Unigene: 657695 Human
    • Unigene: 28534 Mouse
    • Unigene: 482664 Mouse
    see all
  • Alternative names

    • dJ523E19.1 antibody
    • FLJ10775 antibody
    • FLJ11834 antibody
    • LANO adapter protein antibody
    • LAP and no PDZ protein antibody
    • Leucine rich repeat containing protein 1 antibody
    • Leucine-rich repeat-containing protein 1 antibody
    • Lrrc1 antibody
    • LRRC1_HUMAN antibody
    see all

Images

  • Western blot - Anti-Lano antibody (ab127568)
    Western blot - Anti-Lano antibody (ab127568)
    Anti-Lano antibody (ab127568) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size: 59 kDa



    7.5% SDS PAGE
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lano antibody (ab127568)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lano antibody (ab127568)
    ab127568, at 1/250 dilution, staining Lano in paraffin embedded Human breast carcinoma tissue by Immunohistochemistry.

Protocols

  • Western blot protocols
  • Immunohistochemistry protocols

Click here to view the general protocols

Datasheets and documents

  • SDS download

  • Datasheet download

    Download

References (0)

Publishing research using ab127568? Please let us know so that we can cite the reference in this datasheet.

ab127568 has not yet been referenced specifically in any publications.

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