Overview

  • Product name

    Lanosterol, Steroid bioprecursor
  • Description

    Steroid bioprecursor. CYP51A1 component.
  • Biological description

    Steroid bioprecursor. CYP51A1 component. Cholesterol (ab142501) precursor. Shows anti-inflammatory effects in vivo.
  • Purity

    > 55%
  • CAS Number

    79-63-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
  • Molecular weight

    426.72
  • Molecular formula

    C30H50O
  • PubChem identifier

    246983
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bruce A & Rybak AP CYB5D2 requires heme-binding to regulate HeLa cell growth and confer survival from chemotherapeutic agents. PLoS One 9:e86435 (2014). Read more (PubMed: 24466094) »
  • Ma L  et al. Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus. Food Chem 139:503-8 (2013). Read more (PubMed: 23561137) »
  • Lewinska M  et al. Polymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure. PLoS One 8:e82554 (2013). Read more (PubMed: 24358204) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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