Overview

  • Product name

    Anti-LAPTM4B antibody [CL5287]
    See all LAPTM4B primary antibodies
  • Description

    Mouse monoclonal [CL5287] to LAPTM4B
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Synthetic peptide corresponding to Human LAPTM4B aa 290-309.
    Sequence:

    DTTVLLPPYDDATVNGAAKE


    Database link: Q86VI4

  • Positive control

    • IHC-P: Human kidney, heart muscle, testis and skeletal muscle fibre tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 40% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    Purified from TCS.
  • Clonality

    Monoclonal
  • Clone number

    CL5287
  • Isotype

    IgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab242372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has an active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
  • Cellular localization

    Endomembrane system; Multi pass membrane protein.
  • Database links

  • Alternative names

    • LAPTM4beta antibody
    • LC27 antibody
    • Lysosomal associated protein transmembrane 4 beta antibody
    • Lysosomal associated transmembrane protein 4 beta antibody
    • Lysosomal associated transmembrane protein 4B antibody
    • Lysosomal protein transmembrane 4 beta antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human kidney tissue stained for LAPTM4B with ab242372 at a 1:200 dilution in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human heart muscle tissue stained for LAPTM4B with ab242372 at a 1:200 dilution in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human testis tissue stained for LAPTM4B with ab242372 at a 1:200 dilution in immunohistochemical analysis.

  • Negative control - Formalin-fixed, paraffin-embedded human salivary gland (glandular cells) tissue stained for LAPTM4B with ab242372 at a 1:200 dilution in immunohistochemical analysis. Skeletal muscle fibres are positively stained.

References

ab242372 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab242372.
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