Overview

  • Product name

  • Description

    Rabbit polyclonal to LAR
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human LAR aa 688-970.
    Database link: P10586

  • Positive control

    • IHC-P: Human lung and small intestine tissue. ICC/IF: HepG2 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab238600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/20 - 1/200.

Target

  • Function

    Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).
    The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
    Contains 8 fibronectin type-III domains.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 tyrosine-protein phosphatase domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ43335 antibody
    • FLJ45062 antibody
    • FLJ45567 antibody
    • LAR antibody
    • LAR protein antibody
    • LARFN5C antibody
    • LARS antibody
    • LCA homolog antibody
    • Leukocyte antigen related (LAR) PTP receptor antibody
    • Leukocyte antigen related antibody
    • Leukocyte antigen related PTP receptor antibody
    • Leukocyte antigen related tyrosine phosphatase antibody
    • Leukocyte common antigen related antibody
    • Protein Tyrosine Phosphatase Receptor Type F antibody
    • Protein tyrosine phosphatase receptor type F polypeptide antibody
    • Ptprf antibody
    • PTPRF protein antibody
    • PTPRF_HUMAN antibody
    • Receptor linked protein tyrosine phosphatase LAR antibody
    • Receptor type tyrosine protein phosphatase F antibody
    • Receptor type tyrosine protein phosphatase F precursor antibody
    • Receptor-type tyrosine-protein phosphatase F antibody
    see all

Images

  • HepG2 (human liver hepatocellular carcinoma cell line) cells stained for LAR using ab238600 at a dilution of 1/100 in ICC/IF.
    The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal goat serum. The cells were then incubated with the primary antibody overnight at 4°C. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L). Counterstained with DAPI.

  • Paraffin-embedded human lung tissue stained for LAR with ab238600 at a 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human small intestine tissue stained for LAR with ab238600 at a 1/100 dilution in immunohistochemical analysis.

References

ab238600 has not yet been referenced specifically in any publications.

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