Overview

  • Product name

    Lariatin A, antimycobacterial agent
  • Description

    Potent antimycobacterial agent
  • Biological description

    Potent antimycobacterial agent. Contains a lasso structure. Lariatin B analog. Inhibits the growth of Mycobacterium smegmatis (MIC = 3 μM) and Mycobacterium tuberculosis (MIC = 0.2 μM). Shows antimycobacterial effects in vivo.
  • Purity

    > 95%
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Iwatsuki M  et al. Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity. Bioorg Med Chem Lett 19:2888-90 (2009). Read more (PubMed: 19362475) »
  • Iwatsuki M  et al. Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171. J Antibiot (Tokyo) 60:357-63 (2007). Read more (PubMed: 17617692) »
  • Iwatsuki M  et al. Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure. J Am Chem Soc 128:7486-91 (2006). Read more (PubMed: 16756302) »

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