Overview

  • Product name

  • Description

    Rabbit polyclonal to Lass5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide surrounding amino acid 186 of human Lass5

  • Positive control

    • Jurkate cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab63927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 46 kDa).

Target

  • Function

    May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
    Contains 1 TLC (TRAM/LAG1/CLN8) domain.
  • Cellular localization

    Nucleus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CerS5 antibody
    • FLJ25304 antibody
    • LAG1 homolog ceramide synthase 5 antibody
    • LAG1 longevity assurance homolog 5 antibody
    • Lass5 antibody
    • LASS5_HUMAN antibody
    • MGC45411 antibody
    • Trh4 antibody
    see all

Images

  • Anti-Lass5 antibody (ab63927) at 0.5 µg/ml + Jurkat cell lysate

    Predicted band size: 46 kDa
    Observed band size: 25 kDa
    why is the actual band size different from the predicted?
    Additional bands at: 40 kDa (possible isoform), 50 kDa (possible isoform)

References

ab63927 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

Thank you for contacting us.

The link to the Human Protein Atlas for Lass5 is:

http://www.proteinatlas.org/ENSG00000139624

Please let me know which tissue/cells you would be interested inas negative control and I'd be happy to check if we carry such lysates.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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