Key features and details
- Rabbit polyclonal to Lass5
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Lass5 antibody
See all Lass5 primary antibodies
DescriptionRabbit polyclonal to Lass5
Specificityab73289 may cross-react with the highly homologous Lass6.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
An 18 amino acid peptide near the amino terminus of human Lass5
- Rat brain tissue lysate.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab73289 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).|
|IHC-P||Use a concentration of 2.5 µg/ml.|
FunctionMay be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.
Sequence similaritiesContains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Cellular localizationNucleus membrane. Endoplasmic reticulum membrane.
- Information by UniProt
- CerS5 antibody
- FLJ25304 antibody
- LAG1 homolog ceramide synthase 5 antibody
Lane 1 : Anti-Lass5 antibody (ab73289) at 1 µg/ml
Lane 2 : Anti-Lass5 antibody (ab73289) at 2 µg/ml
All lanes : rat brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 46 kDa
Observed band size: 46 kDa
ab73289 at 2.5µg/ml staining Lass5 in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections).
Immunofluorescence of LASS5 in Human Brain cells using ab73289 at 20 ug/ml.
ab73289 has been referenced in 1 publication.
- Ji R et al. Increased de novo ceramide synthesis and accumulation in failing myocardium. JCI Insight 2:N/A (2017). WB ; Human . PubMed: 28469091