Validated using a knockout cell line

Recombinant Anti-LC3B antibody [EPR18709] - Autophagosome Marker (ab192890)

Knockout Tested Rabbit recombinant monoclonal LC3B antibody [EPR18709]. Validated in WB, IP, ICC/IF and tested in Mouse, Rat, Human. Cited in 21 publication(s). Independently reviewed in 11 review(s).

Publishing research using ab192890? Please let us know so that we can cite the reference in this datasheet.

ab192890 has been referenced in 37 publications.

  • Wang Z  et al. Taurine protected As2O3-induced the activation of hepatic stellate cells through inhibiting PPARa-autophagy pathway. Chem Biol Interact 300:123-130 (2019). PubMed: 30677399
  • Mai CT  et al. Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation. Mol Immunol 105:76-85 (2019). PubMed: 30496979
  • Peng Y  et al. TRIM28 activates autophagy and promotes cell proliferation in glioblastoma. Onco Targets Ther 12:397-404 (2019). PubMed: 30655676
  • Wang L  et al. miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway. Int J Mol Med 43:1373-1381 (2019). PubMed: 30664152
  • Yang Y  et al. Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma. Cell Death Dis 10:41 (2019). PubMed: 30674868
  • Tang T  et al. Exogenous Netrin-1 Inhibits Autophagy of Ischemic Brain Tissues and Hypoxic Neurons via PI3K/mTOR Pathway in Ischemic Stroke. J Stroke Cerebrovasc Dis 28:1338-1345 (2019). PubMed: 30797642
  • Li C  et al. TLR2 promotes development and progression of human glioma via enhancing autophagy. Gene 700:52-59 (2019). PubMed: 30898699
  • Ren Z  et al. Inhibition of human glioblastoma cell invasion involves PION@E6 mediated autophagy process. Cancer Manag Res 11:2643-2652 (2019). PubMed: 31015768
  • Li W  et al. Vitamin K2 stimulates MC3T3-E1 osteoblast differentiation and mineralization through autophagy induction. Mol Med Rep 19:3676-3684 (2019). PubMed: 30896842
  • Zhang P  et al. Combination of 3-methyladenine therapy and Asn-Gly-Arg (NGR)-modified mesoporous silica nanoparticles loaded with temozolomide for glioma therapy in vitro. Biochem Biophys Res Commun 509:549-556 (2019). PubMed: 30600180
  • Xu Z  et al. UBIAD1 suppresses the proliferation of bladder carcinoma cells by regulating H-Ras intracellular trafficking via interaction with the C-terminal domain of H-Ras. Cell Death Dis 9:1170 (2018). PubMed: 30518913
  • Zhu S  et al. Effects of autophagy on the spermatogonia of chronic hypoxic mice. Am J Transl Res 10:4119-4129 (2018). PubMed: 30662655
  • Wang Y  et al. Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia. Oxid Med Cell Longev 2018:4612727 (2018). PubMed: 30662583
  • Su Y  et al. Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway. Mol Med Rep 18:5445-5454 (2018). PubMed: 30365078
  • Wu J  et al. Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation. J Exp Clin Cancer Res 37:272 (2018). PubMed: 30413206
  • Yi C  et al. Dexmedetomidine on autophagy of hippocampal neurons in aged rats under sevoflurane anesthesia. Exp Ther Med 16:837-841 (2018). PubMed: 30112038
  • Qiu T  et al. Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway. Cell Death Dis 9:946 (2018). PubMed: 30237538
  • Liu CY  et al. LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription. Nat Commun 9:29 (2018). WB ; Mouse . PubMed: 29295976
  • Yuan J  et al. Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway. Int J Mol Med 41:2086-2098 (2018). PubMed: 29344647
  • Yan X  et al. Lup-20(29)-en-3ß,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria. Cell Death Dis 9:241 (2018). PubMed: 29445224
  • Zheng YY  et al. Autophagy activation by Jiang Zhi Granule protects against metabolic stress-induced hepatocyte injury. World J Gastroenterol 24:992-1003 (2018). PubMed: 29531463
  • Puri C  et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell 45:114-131.e8 (2018). ICC/IF . PubMed: 29634932
  • Peng S  et al. Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy. Front Pharmacol 9:438 (2018). PubMed: 29773990
  • Wang P  et al. Knockdown of NUP160 inhibits cell proliferation, induces apoptosis, autophagy and cell migration, and alters the expression and localization of podocyte associated molecules in mouse podocytes. Gene 664:12-21 (2018). WB . PubMed: 29704630
  • Huang F  et al. LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis. Mol Cancer 17:98 (2018). PubMed: 30001707
  • Liu F  et al. miR-92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2. Int J Oncol 53:1505-1515 (2018). PubMed: 30066891
  • Meng D  et al. Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells. Biomed Pharmacother 108:1617-1627 (2018). PubMed: 30372864
  • Xia Y  et al. YiQiFuMai lyophilized injection attenuates particulate matter-induced acute lung injury in mice via TLR4-mTOR-autophagy pathway. Biomed Pharmacother 108:906-913 (2018). PubMed: 30372902
  • Zhu B  et al. Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism. Vascul Pharmacol N/A:N/A (2018). PubMed: 30447331
  • Xiao T  et al. RACK1 promotes tumorigenicity of colon cancer by inducing cell autophagy. Cell Death Dis 9:1148 (2018). PubMed: 30451832
  • Zhu JF  et al. Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation. Cell Death Dis 9:1154 (2018). PubMed: 30459351
  • Chiang MH  et al. Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase. Front Pharmacol 8:819 (2017). IHC-P, ICC/IF ; Mouse, Rat . PubMed: 29184499
  • Wang L  et al. Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway. Sci Rep 7:5384 (2017). PubMed: 28710412
  • Hu D  et al. Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts. Sci Rep 7:13554 (2017). PubMed: 29051574
  • Jiang L  et al. Similarity in the functions of HIF-1a and HIF-2a proteins in cervical cancer cells. Oncol Lett 14:5643-5651 (2017). PubMed: 29098039
  • Ma Y  et al. RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation. Oncotarget 8:53084-53099 (2017). PubMed: 28881795
  • Zhang J  et al. Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells. Cell Death Dis 8:e2954 (2017). PubMed: 28749469

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