Anti-LDB2 antibody (ab3627)
Key features and details
- Rabbit polyclonal to LDB2
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-LDB2 antibody -
Description
Rabbit polyclonal to LDB2 -
Host species
Rabbit -
Specificity
This antibody detects a single clean band representing LDB2 at 42kD in human kidney and mouse spleen. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Chicken -
Immunogen
Synthetic peptide:
SKESYHNSSITVDC
conjugated to KLH, corresponding to amino acids 107-120 of Human LDB2. -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab3627 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Notes |
---|
WB: 1/500. Detects a band of approximately 42 kDa (predicted molecular weight: 42.7 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. -
Sequence similarities
Belongs to the LDB family. -
Post-translational
modificationsUbiquitinated by RLIM/RNF12, leading to its degradation by the proteasome. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 395631 Chicken
- Entrez Gene: 9079 Human
- Entrez Gene: 16826 Mouse
- Omim: 603450 Human
- SwissProt: Q9W676 Chicken
- SwissProt: O43679 Human
- SwissProt: O55203 Mouse
- Unigene: 714330 Human
see all -
Alternative names
- Carboxyl terminal LIM domain binding protein 1 antibody
- Carboxyl terminal LIM domain protein 1 antibody
- Carboxyl-terminal LIM domain-binding protein 1 antibody
see all
Images
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Western blot using ab3627 at 1/500.
Lane 1: Human Kidney
Lane 2: Mouse SpleenLysates at 18
µ g per lane.
Secondary ab: Goat polyclonal to Rabbit IgG H&L (HRP) Pre-Adsorbed
ab7090 (1/5000).
Exposure time: 1 minute.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab3627 has been referenced in 2 publications.
- Cheng L et al. Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells. Commun Biol 4:1039 (2021). PubMed: 34489520
- Storbeck CJ et al. The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration. Mol Biol Cell 20:4174-82 (2009). ICC/IF ; Mouse . PubMed: 19675209