Overview

  • Product name
    Anti-LDL antibody
    See all LDL primary antibodies
  • Description
    Chicken polyclonal to LDL
  • Host species
    Chicken
  • Tested applications
    Suitable for: ELISA, RIAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human LDL purified from Human plasma.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab157795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • Relevance
    The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells
  • Cellular localization
    Cell Membrane
  • Alternative names
    • low density lipoprotein antibody

References

ab157795 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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