Anti-LDL antibody (ab157795)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-LDL antibody
See all LDL primary antibodies -
Description
Chicken polyclonal to LDL -
Host species
Chicken -
Tested applications
Suitable for: ELISA, RIAmore details -
Species reactivity
Reacts with: Human -
Immunogen
Human LDL purified from Human plasma.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.50
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
Purity
Protein L purified -
Clonality
Polyclonal -
Isotype
IgY -
Research areas
Associated products
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab157795 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | Use at an assay dependent dilution. | |
| RIA | Use at an assay dependent dilution. |
Target
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Relevance
The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells -
Cellular localization
Cell Membrane -
Alternative names
- low density lipoprotein antibody
Datasheets and documents
References
ab157795 has not yet been referenced specifically in any publications.
