Overview

  • Product name

    Anti-LDL antibody (Biotin)
    See all LDL primary antibodies
  • Description

    Chicken polyclonal to LDL (Biotin)
  • Host species

    Chicken
  • Conjugation

    Biotin
  • Tested applications

    Suitable for: ELISA, RIAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Human LDL purified from Human plasma.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab157800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
RIA Use at an assay dependent dilution.

Target

  • Relevance

    The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells
  • Cellular localization

    Cell Membrane
  • Alternative names

    • low density lipoprotein antibody

References

This product has been referenced in:

  • Lee G  et al. Single Microfluidic Electrochemical Sensor System for Simultaneous Multi-Pulmonary Hypertension Biomarker Analyses. Sci Rep 7:7545 (2017). Read more (PubMed: 28790334) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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