Anti-LDL Receptor antibody [EP1553Y] (ab52818)

Publishing research using ab52818? Please let us know so that we can cite the reference in this datasheet.

ab52818 has been referenced in 42 publications.

  • Zhu L  et al. Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding. Mol Metab 8:106-116 (2018). WB . PubMed: 29331506
  • Xie Z  et al. Adipose-Derived Exosomes Exert Proatherogenic Effects by Regulating Macrophage Foam Cell Formation and Polarization. J Am Heart Assoc 7:N/A (2018). PubMed: 29502100
  • Yang SH  et al. Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism. Cardiovasc Diabetol 17:48 (2018). PubMed: 29618348
  • Ding W  et al. Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. JCI Insight 3:N/A (2018). PubMed: 29563333
  • Alberti D  et al. An innovative therapeutic approach for malignant mesothelioma treatment based on the use of Gd/boron multimodal probes for MRI guided BNCT. J Control Release 280:31-38 (2018). Mouse . PubMed: 29730155
  • Gallagher EJ  et al. Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer growth in mouse models of hyperlipidemia. Oncogene 36:6462-6471 (2017). IHC . PubMed: 28759039
  • Sobot D  et al. Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery. Nat Commun 8:15678 (2017). WB ; Human . PubMed: 28555624
  • Rondón-Ortiz AN  et al. High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells. Front Pharmacol 8:772 (2017). PubMed: 29201005
  • Rocchi A  et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet 13:e1006962 (2017). PubMed: 28806762
  • Gustafsen C  et al. Heparan sulfate proteoglycans present PCSK9 to the LDL receptor. Nat Commun 8:503 (2017). PubMed: 28894089
  • Rajora MA  et al. Tailored theranostic apolipoprotein E3 porphyrin-lipid nanoparticles target glioblastoma. Chem Sci 8:5371-5384 (2017). PubMed: 28970916
  • Peng L  et al. QiShenYiQi pill attenuates atherosclerosis by promoting regulatory T cells, inhibiting T helper 17 cells and accelerating cholesterol excretion. Oncotarget 8:82196-82206 (2017). WB . PubMed: 29137256
  • Pinkosky SL  et al. Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis. Nat Commun 7:13457 (2016). PubMed: 27892461
  • Jensen KK  et al. Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey. J Lipid Res 57:2150-2162 (2016). WB ; Mouse . PubMed: 27707816
  • Zhong CY  et al. Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice. Sci Rep 5:10512 (2015). WB ; Mouse . PubMed: 26015368
  • Guan HP  et al. Glucagon receptor antagonism induces increased cholesterol absorption. J Lipid Res 56:2183-95 (2015). PubMed: 26373568
  • Meng ZX  et al. A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis. Cell Rep 13:1658-69 (2015). PubMed: 26586440
  • de Gonzalo-Calvo D  et al. Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study. BMC Cancer 15:460 (2015). WB ; Human . PubMed: 26055977
  • Marshall SM  et al. Reduction of VLDL secretion decreases cholesterol excretion in niemann-pick C1-like 1 hepatic transgenic mice. PLoS One 9:e84418 (2014). WB ; Mouse . PubMed: 24404162
  • Kanai Y  et al. KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae. J Cell Biol 204:395-408 (2014). Mouse . PubMed: 24469637
  • Niesman IR  et al. Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice. J Neuroinflammation 11:39 (2014). WB ; Mouse . PubMed: 24593993
  • Hu YW  et al. A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis. J Lipid Res 55:681-97 (2014). PubMed: 24493833
  • Pedrelli M  et al. Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice. PLoS One 9:e93552 (2014). WB ; Mouse . PubMed: 24695360
  • Davis BT  et al. Targeted disruption of LDLR causes hypercholesterolemia and atherosclerosis in Yucatan miniature pigs. PLoS One 9:e93457 (2014). WB ; Pig . PubMed: 24691380
  • Yamashita T  et al. Strong improvement of apolipoprotein e/low-density lipoprotein receptor signals by telmisartan in poststroke spontaneously hypertensive stroke resistant. J Stroke Cerebrovasc Dis 23:2240-9 (2014). PubMed: 25174563
  • Nagajyothi F  et al. High fat diet modulates Trypanosoma cruzi infection associated myocarditis. PLoS Negl Trop Dis 8:e3118 (2014). WB ; Mouse . PubMed: 25275627
  • Scotti E  et al. IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Mol Cell Biol 33:1503-14 (2013). PubMed: 23382078
  • Cal R  et al. Aggregated low-density lipoprotein induces LRP1 stabilization through E3 ubiquitin ligase CHFR downregulation in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 33:369-77 (2013). WB ; Human . PubMed: 23241409
  • Tveten K  et al. PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment. J Lipid Res 54:1560-6 (2013). PubMed: 23509406
  • Sorrentino V  et al. The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation. J Lipid Res 54:2174-84 (2013). WB ; Human . PubMed: 23733886
  • Vázquez-Medina JP  et al. Prolonged fasting activates Nrf2 in post-weaned elephant seals. J Exp Biol 216:2870-8 (2013). PubMed: 23619404
  • Pietiäinen V  et al. NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation. J Cell Sci 126:3961-71 (2013). WB ; Mouse . PubMed: 23813961
  • Berre S  et al. CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells. J Exp Med 210:2523-38 (2013). Human . PubMed: 24145510
  • Nagajyothi F  et al. Curcumin treatment provides protection against Trypanosoma cruzi infection. Parasitol Res 110:2491-9 (2012). PubMed: 22215192
  • Cihil KM  et al. Disabled-2 Protein Facilitates Assembly Polypeptide-2-independent Recruitment of Cystic Fibrosis Transmembrane Conductance Regulator to Endocytic Vesicles in Polarized Human Airway Epithelial Cells. J Biol Chem 287:15087-99 (2012). WB . PubMed: 22399289
  • Lin JZ  et al. Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor. Endocrinology 153:6136-44 (2012). PubMed: 23087171
  • Nagajyothi F  et al. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. PLoS Negl Trop Dis 5:e953 (2011). WB, ICC/IF ; Human . PubMed: 21408103
  • Scotti E  et al. Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists. Mol Cell Biol 31:1885-93 (2011). WB ; Mouse . PubMed: 21343340
  • Thysell E  et al. Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. PLoS One 5:e14175 (2010). IHC-P ; Human . PubMed: 21151972
  • Matsui M  et al. Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter. Chem Biol 17:1344-55 (2010). WB, ICC/IF ; Human . PubMed: 21168770
  • Kim N  et al. Lrp4 is a receptor for Agrin and forms a complex with MuSK. Cell 135:334-42 (2008). WB ; Human . PubMed: 18848351
  • Dong M  et al. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. Mol Biol Cell 19:5226-37 (2008). WB . PubMed: 18815274


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