Overview

  • Product name

  • Description

    Mouse monoclonal to LEC
  • Host species

    Mouse
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant hLEC

  • Positive control

    • Recombinant human LEC protein (ab627) can be used as a positive control in WB.
  • General notes

    Monoclonal antibodies were produced in BALB/c X ICR F1 mice.

Properties

  • Form

    Lyophilised:Reconstitute with 500µl of sterile water.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    Sterile filtered.
  • Clonality

    Monoclonal
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
In a sandwich ELISA (assuming 100µl/well), a concentration of 1-2 µg/ml of this antibody will detect at least 0.03ng/well of recombinant human LEC.

Target

  • Function

    Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
  • Tissue specificity

    Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C-C motif chemokine 16 antibody
    • CCL16 antibody
    • CCL16_HUMAN antibody
    • Chemokine (C-C motif) ligand 16 antibody
    • Chemokine CC-4 antibody
    • Chemokine LEC antibody
    • CKb12 antibody
    • HCC-4 antibody
    • HCC4 antibody
    • IL-10-inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • ILINCK antibody
    • LCC-1 antibody
    • LCC1 antibody
    • Liver CC chemokine 1 precursor antibody
    • Liver expressed chemokine antibody
    • Liver-expressed chemokine antibody
    • LMC antibody
    • Lymphocyte and monocyte chemoattractant antibody
    • Monotactin 1 antibody
    • Monotactin-1 antibody
    • MTN-1 antibody
    • Mtn1 antibody
    • NCC-4 antibody
    • NCC4 antibody
    • New CC chemokine 4 antibody
    • SCYA16 antibody
    • SCYL4 antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
    • Small-inducible cytokine A16 antibody
    see all

References

ab628 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab628.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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