Overview

  • Product name

    Anti-LEC antibody - C-terminal
    See all LEC primary antibodies
  • Description

    Rabbit polyclonal to LEC - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human LEC (C terminal). NP_004581.
    Database link: O15467

  • Positive control

    • HepG2 cell lysate; Human lymphoma tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab199162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB 1/500 - 1/2000. Predicted molecular weight: 14 kDa.

Target

  • Function

    Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
  • Tissue specificity

    Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C-C motif chemokine 16 antibody
    • CCL16 antibody
    • CCL16_HUMAN antibody
    • Chemokine (C-C motif) ligand 16 antibody
    • Chemokine CC-4 antibody
    • Chemokine LEC antibody
    • CKb12 antibody
    • HCC-4 antibody
    • HCC4 antibody
    • IL-10-inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • ILINCK antibody
    • LCC-1 antibody
    • LCC1 antibody
    • Liver CC chemokine 1 precursor antibody
    • Liver expressed chemokine antibody
    • Liver-expressed chemokine antibody
    • LMC antibody
    • Lymphocyte and monocyte chemoattractant antibody
    • Monotactin 1 antibody
    • Monotactin-1 antibody
    • MTN-1 antibody
    • Mtn1 antibody
    • NCC-4 antibody
    • NCC4 antibody
    • New CC chemokine 4 antibody
    • SCYA16 antibody
    • SCYL4 antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
    • Small-inducible cytokine A16 antibody
    see all

Images

  • Anti-LEC antibody - C-terminal (ab199162) at 1/760 dilution + HepG2 cell lysate at 40 µg

    Predicted band size: 14 kDa


    Exposure time: 3 seconds


    15% SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue labeling LEC with ab199162 at 1/50 dilution.

References

ab199162 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab199162.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up