Overview

  • Product name

    Anti-Leishmania A2 antibody [C9]
  • Description

    Mouse monoclonal [C9] to Leishmania A2
  • Host species

    Mouse
  • Specificity

    ab150344 recognizes only the amastigote form of the A2 protein of Leishmania donovani and infantum. There is no cross reactivity with other Leishmania species. ab150344 recognizes the family of A2 proteins ranging from 42 to 100kDa.
  • Tested applications

    Suitable for: WB, IP, ICC/IFmore details
  • Species reactivity

    Reacts with: Leishmania
  • Immunogen

    A2 protein from Leishmania donovani and infantum. Specific for amastigote stage

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Constituent: 99% PBS
    Note: Contains no additives.
  • Concentration information loading...
  • Purity

    Concentrated Culture Supernatant
  • Clonality

    Monoclonal
  • Clone number

    C9
  • Isotype

    IgG1

Applications

Our Abpromise guarantee covers the use of ab150344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100.
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • Relevance

    Leishmania donovani protozoa is responsible for human visceral leishmaniasis. During their life cycle, the parasites exist in 2 forms: as flagellated promastigote within the sandfly vector and as non flagellated amastigote in the macrophage phagolysosomal compartment of the mammalian host. A2 protein is an amastigote specific virulence factor that is required for Leishmania donovani parasite survival in a mammalian host.

References

This product has been referenced in:

  • Domínguez-Bernal G  et al. HisAK70: progress towards a vaccine against different forms of leishmaniosis. Parasit Vectors 8:629 (2015). Read more (PubMed: 26653170) »
See 1 Publication for this product

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