Overview

  • Product name

  • Description

    Rabbit polyclonal to LEO1/RDL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human LEO1/RDL.
    Database link: Q8WVC0

  • Positive control

    • WB: HeLa nuclear extract.
  • General notes

     This product was previously labelled as LEO1

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
  • Purity

    Whole antiserum
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab230403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 75, 68 kDa.

Target

  • Function

    The PAF1 complex is a multifunctional complex. The PAF1 complex interacts with POLR2A. May be involved in both initiation and elongation, histone methylation and RNA processing. Overexpression of LEO1 induces cell growth arrest and premature senescence of fibroblasts.
  • Tissue specificity

    Highly expressed in skeletal muscle and heart. Weakly expressed in placenta and liver.
  • Sequence similarities

    Belongs to the LEO1 family.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Gm185 antibody
    • LEO1 antibody
    • LEO1_HUMAN antibody
    • LOC123439 antibody
    • Paf1/RNA polymerase II complex component antibody
    • Replicative senescence down regulated leo1 like protein antibody
    • Replicative senescence down-regulated leo1-like protein antibody
    • Replicative senescence downregulated leo1 like antibody
    • RNA polymerase associated protein LEO1 antibody
    • RNA polymerase-associated protein LEO1 antibody
    • Senescence downregulated leo1 like antibody
    see all

Images

  • Anti-LEO1/RDL antibody (ab230403) at 1/1000 dilution + HeLa (human epithelial cell line from cervix adenocarcinoma) nuclear extract at 20 µg

    Developed using the ECL technique.

    Predicted band size: 75, 68 kDa

References

ab230403 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230403.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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