Key features and details
- Rabbit polyclonal to Leukotriene B4 Receptor/BLT
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Leukotriene B4 Receptor/BLT antibody
See all Leukotriene B4 Receptor/BLT primary antibodies
DescriptionRabbit polyclonal to Leukotriene B4 Receptor/BLT
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: CowDoes not react with: Mouse
- Human spleen and tonsil tissues.
This product was previously labelled as Leukotriene B4 Receptor
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% Tris buffered saline, 50% Glycerol, 0.05% BSA
Concentration information loading...
PurityProtein A purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
Our Abpromise guarantee covers the use of ab133185 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionReceptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Tissue specificityExpressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
modificationsPhosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
Cellular localizationCell membrane.
- Information by UniProt
- BLT antibody
- BLT1 antibody
- BLTR antibody
Immunohistochemical analysis of paraffin embedded Human spleen tissue labelling Leukotriene B4 Receptor/BLT with ab133185 antibody at a concentration of 5 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelling Leukotriene B4 Receptor/BLT with ab133185 antibody at a concentration of 5 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
ab133185 has not yet been referenced specifically in any publications.