Overview

  • Product name

    Anti-Leukotriene B4 Receptor/BLT antibody
    See all Leukotriene B4 Receptor/BLT primary antibodies
  • Description

    Rabbit polyclonal to Leukotriene B4 Receptor/BLT
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Horse, Monkey, Gorilla, Opossum, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human Leukotriene B4 Receptor/BLT (C terminal). (BAA20424.1)

  • Positive control

    • Human spleen tissue.
  • General notes

     This product was previously labelled as Leukotriene B4 Receptor

     

Properties

Applications

Our Abpromise guarantee covers the use of ab140832 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
  • Tissue specificity

    Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BLT antibody
    • BLT1 antibody
    • BLTR antibody
    • Chemoattractant receptor-like 1 antibody
    • Chemokine receptor like 1 antibody
    • CMKRL1 antibody
    • G protein coupled receptor 16 antibody
    • G-protein coupled receptor 16 antibody
    • GPR16 antibody
    • Leukotriene B4 G Protein coupled receptor antibody
    • Leukotriene B4 receptor 1 antibody
    • Leukotriene B4 receptor antibody
    • LT4R1_HUMAN antibody
    • LTB4 R 1 antibody
    • LTB4-R 1 antibody
    • LTB4-R1 antibody
    • LTB4R 1 antibody
    • Ltb4r antibody
    • LTB4R1 antibody
    • LTBR1 antibody
    • P2RY7 antibody
    • P2Y purinoceptor 7 antibody
    • P2Y7 antibody
    • Purinergic receptor P2Y G protein coupled 7 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen tissue (red pulp) labelling Leukotriene B4 Receptor/BLT with ab140832 at 4 μg/ml.

References

ab140832 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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