Anti-Leukotriene B4 Receptor/BLT antibody - Cytoplasmic domain (ab188886)


  • Product name

    Anti-Leukotriene B4 Receptor/BLT antibody - Cytoplasmic domain
    See all Leukotriene B4 Receptor/BLT primary antibodies
  • Description

    Rabbit polyclonal to Leukotriene B4 Receptor/BLT - Cytoplasmic domain
  • Host species

  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Hamster, Cow, Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide within Human Leukotriene B4 Receptor/BLT (internal sequence). The exact sequence is proprietary. 16 amino acid peptide from 3rd cytoplasmic domain.
    Database link: Q15722

  • Positive control

    • Human spleen tissue.
  • General notes

     This product was previously labelled as Leukotriene B4 Receptor




Our Abpromise guarantee covers the use of ab188886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Function

    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
  • Tissue specificity

    Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational

    Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BLT antibody
    • BLT1 antibody
    • BLTR antibody
    • Chemoattractant receptor-like 1 antibody
    • Chemokine receptor like 1 antibody
    • CMKRL1 antibody
    • G protein coupled receptor 16 antibody
    • G-protein coupled receptor 16 antibody
    • GPR16 antibody
    • Leukotriene B4 G Protein coupled receptor antibody
    • Leukotriene B4 receptor 1 antibody
    • Leukotriene B4 receptor antibody
    • LT4R1_HUMAN antibody
    • LTB4 R 1 antibody
    • LTB4-R 1 antibody
    • LTB4-R1 antibody
    • LTB4R 1 antibody
    • Ltb4r antibody
    • LTB4R1 antibody
    • LTBR1 antibody
    • P2RY7 antibody
    • P2Y purinoceptor 7 antibody
    • P2Y7 antibody
    • Purinergic receptor P2Y G protein coupled 7 antibody
    see all


  • Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded human spleen tissue sections (red pulp) labeling Leukotriene B4 Receptor/BLT using ab188886 at 10 µg/ml.


ab188886 has not yet been referenced specifically in any publications.

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