Overview

  • Product name

    Leukotriene D4, CysLT1 and CysLT2 receptor agonist
  • Description

    Potent, selective CysLT1 and CysLT2 receptor agonist
  • Biological description

    Potent, selective CysLT1 and CysLT2 receptor agonist (EC50 values are 1.12 and 0.99 nM, respectively. Induces bronchoconstriction and vasoconstriction. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    73836-78-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Wunder F  et al. Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor. Br J Pharmacol 160:399-409 (2010). Read more (PubMed: 20423349) »
  • Wang CG  et al. Role of leukotriene D4 in allergen-induced increases in airway smooth muscle in the rat. Am Rev Respir Dis 148:413-7 (1993). Read more (PubMed: 8342905) »
  • Ahmed T  et al. Direct and indirect effects of leukotriene D4 on the pulmonary and systemic circulations. Am Rev Respir Dis 131:554-8 (1985). Read more (PubMed: 2986501) »

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