Overview

  • Product name

    Levamisole hydrochloride, Alkaline phosphatase inhibitor
  • Description

    Alkaline phosphatase inhibitor. Selective agonist at nematode nAChRs.
  • Biological description

    Alkaline phosphatase inhibitor. Also a selective agonist at nematode nicotinic acetylcholine receptors (nAChRs). Displays anticancer, immunomodulatory and antiparasitic activity.
  • Purity

    > 99%
  • CAS Number

    16595-80-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hegde M  et al. Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice. PLoS One 7:e43632 (2012). Read more (PubMed: 22970136) »
  • Rayes D  et al. Molecular basis of the differential sensitivity of nematode and mammalian muscle to the anthelmintic agent levamisole. J Biol Chem 279:36372-81 (2004). Read more (PubMed: 15201284) »
  • Trailovic SM  et al. Levamisole receptor phosphorylation: effects of kinase antagonists on membrane potential responses in Ascaris suum suggest that CaM kinase and tyrosine kinase regulate sensitivity to levamisole. J Exp Biol 205:3979-88 (2002). Read more (PubMed: 12432019) »
  • Lewis JA  et al. The levamisole receptor, a cholinergic receptor of the nematode Caenorhabditis elegans. Mol Pharmacol 31:185-93 (1987). Read more (PubMed: 3807894) »

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