Levamisole hydrochloride, Alkaline phosphatase inhibitor (ab141217)
Key features and details
- Alkaline phosphatase inhibitor. Selective agonist at nematode nAChRs.
- CAS Number: 16595-80-5
- Purity: > 99%
- Soluble in DMSO to 100 mM and water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Levamisole hydrochloride, Alkaline phosphatase inhibitor -
Description
Alkaline phosphatase inhibitor. Selective agonist at nematode nAChRs. -
Biological description
Alkaline phosphatase inhibitor. Also a selective agonist at nematode nicotinic acetylcholine receptors (nAChRs). Displays anticancer, immunomodulatory and antiparasitic activity.
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Purity
> 99% -
CAS Number
16595-80-5 -
Chemical structure
Properties
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Chemical name
2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride -
Molecular weight
240.75 -
Molecular formula
C11H12N2S.HCl -
PubChem identifier
68628 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.N1=C3SCCN3C[C@@H]1c2ccccc2 -
Source
Synthetic
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Research areas
Associated products
Images
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Chemical Structure - Levamisole hydrochloride, Alkaline phosphatase inhibitor (ab141217)2D chemical structure image of ab141217, Levamisole hydrochloride, Alkaline phosphatase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab141217 has been referenced in 1 publication.
- Wessely A et al. Induction of ALP and MMP9 activity facilitates invasive behavior in heterogeneous human BMSC and HNSCC 3D spheroids. FASEB J N/A:fj201900925R (2019). PubMed: 31366234