Overview

  • Product name

  • Description

    Rabbit polyclonal to LGR5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human LGR5.
    Database link: O75473

  • Positive control

    • WB: HeLa and HepG2 extracts. Mouse skeletal muscle extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab237598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 99 kDa.

Target

  • Function

    Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.
  • Tissue specificity

    Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
    Contains 16 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FEX antibody
    • G protein coupled receptor 49 antibody
    • G protein coupled receptor 67 antibody
    • g protein-coupled receptor fex antibody
    • G-protein coupled receptor 49 antibody
    • G-protein coupled receptor 67 antibody
    • G-protein coupled receptor HG38 antibody
    • GPCR GPR49 antibody
    • GPR 49 antibody
    • GPR 67 antibody
    • GPR49 antibody
    • GPR67 antibody
    • GRP 49 antibody
    • GRP49 antibody
    • HG 38 antibody
    • HG38 antibody
    • Leucine rich repeat containing G protein coupled receptor 5 antibody
    • Leucine-rich repeat-containing G-protein coupled receptor 5 antibody
    • LGR 5 antibody
    • LGR5 antibody
    • LGR5_HUMAN antibody
    • MGC117008 antibody
    • Orphan G protein coupled receptor HG38 antibody
    see all

Images

  • All lanes : Anti-LGR5 antibody (ab237598) at 1/500 dilution

    Lane 1 : HeLa (Human epithelial cell line from cervix adenocarcinoma) cell extracts
    Lane 2 : HepG2 (Human liver hepatocellular carcinoma cell line) cell extracts
    Lane 3 : Mouse skeletal muscle extracts

    Lysates/proteins at 25 µg per lane.

    Secondary
    All lanes : HRP Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution

    Predicted band size: 99 kDa



    Blocking buffer: 3% non-fat dry milk in TBST.

References

ab237598 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab237598.
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