Product nameAnti-LGR5 antibody
See all LGR5 primary antibodies
DescriptionRabbit polyclonal to LGR5
Tested applicationsSuitable for: IHC-Pmore details
Unsuitable for: ICC/IF
Species reactivityReacts with: Human
Synthetic peptide within Human LGR5 aa 650-700. The exact sequence is proprietary.
Database link: O75473
- IHC-P: Human small intestine.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 30% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab261734 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionOrphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.
Tissue specificityExpressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Contains 16 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
Cellular localizationCell membrane.
- Information by UniProt
- FEX antibody
- G protein coupled receptor 49 antibody
- G protein coupled receptor 67 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab261734 has not yet been referenced specifically in any publications.