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ab75850 has been referenced in 26 publications.

  • Ullmann P  et al. Tumor suppressor miR-215 counteracts hypoxia-induced colon cancer stem cell activity. Cancer Lett 450:32-41 (2019). PubMed: 30790680
  • Yang B  et al. ß-catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa-adenoma-adenocarcinoma sequence of colorectal tumorigenesis. Oncol Lett 15:2287-2295 (2018). PubMed: 29434936
  • Jiang Y  et al. MAP30 promotes apoptosis of U251 and U87 cells by suppressing the LGR5 and Wnt/ß-catenin signaling pathway, and enhancing Smac expression. Oncol Lett 15:5833-5840 (2018). PubMed: 29556310
  • Wang Q  et al. PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer. Cell Death Dis 9:739 (2018). PubMed: 29970892
  • Zhou X  et al. R-Spondin1/LGR5 Activates TGFß Signaling and Suppresses Colon Cancer Metastasis. Cancer Res 77:6589-6602 (2017). PubMed: 28939678
  • Lee SH  et al. Generation of Insulin-Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD. Diabetes Metab J 41:405-416 (2017). IHC-P ; Mouse . PubMed: 29086539
  • Zhu X  et al. Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice. Signal Transduct Target Ther 2:17017 (2017). PubMed: 29263919
  • Lin Y  et al. HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+liver stem cells. Nat Commun 8:1175 (2017). PubMed: 29079780
  • Harada Y  et al. Leucine-rich repeat-containing G protein-coupled receptor 5 and CD133 expression is associated with tumor progression and resistance to preoperative chemoradiotherapy in low rectal cancer. Oncol Lett 14:7791-7798 (2017). IHC-P ; Human . PubMed: 29250176
  • Kantara C  et al. Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis. Lab Invest 95:100-12 (2015). PubMed: 25347154
  • Jardé T  et al. ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer. PLoS One 10:e0138336 (2015). ICC/IF ; Human . PubMed: 26367378
  • Su X  et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep 5:18588 (2015). PubMed: 26687459
  • Morgan RG  et al. Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells. Br J Cancer 112:714-9 (2015). WB . PubMed: 25611300
  • Oshima N  et al. Induction of cancer stem cell properties in colon cancer cells by defined factors. PLoS One 9:e101735 (2014). Flow Cyt ; Human . PubMed: 25006808
  • Bolick DT  et al. Intestinal cell kinase is a novel participant in intestinal cell signaling responses to protein malnutrition. PLoS One 9:e106902 (2014). PubMed: 25184386
  • Tsuji S  et al. The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis. Nat Commun 5:3150 (2014). PubMed: 24452072
  • Xi HQ  et al. Leucine-rich repeat-containing G-protein-coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer. Br J Cancer 110:2011-20 (2014). Human . PubMed: 24594994
  • Janakiram NB  et al. Raloxifene and antiestrogenic gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem-like cells. Cancer Prev Res (Phila) 7:300-9 (2014). PubMed: 24431404
  • Zhou WJ  et al. Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Nature 501:107-11 (2013). IHC (PFA fixed) . PubMed: 23903657
  • Al-Kharusi MR  et al. LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs. Carcinogenesis : (2013). WB ; Human . PubMed: 23349017
  • Femia AP  et al. Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear ß-catenin. BMC Cancer 13:48 (2013). IHC-P ; Rat . PubMed: 23374535
  • Chen T  et al. Distinct Expression Patterns of ICK/MAK/MOK Protein Kinases in the Intestine Implicate Functional Diversity. PLoS One 8:e79359 (2013). Mouse . PubMed: 24244486
  • Petherick KJ  et al. Autolysosomal ß-catenin degradation regulates Wnt-autophagy-p62 crosstalk. EMBO J 32:1903-16 (2013). WB . PubMed: 23736261
  • Wu XS  et al. Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival. World J Surg Oncol 10:244 (2012). IHC-P ; Human . PubMed: 23153436
  • Sei Y  et al. A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine. Am J Physiol Gastrointest Liver Physiol 300:G345-56 (2011). IHC-FrFl ; Mouse . PubMed: 21088235
  • Liu X  et al. Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway. FEBS Lett 584:911-6 (2010). IHC-P ; Mouse . PubMed: 20083111

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