Description

  • Product name

    LGR5 peptide
  • Animal free

    No
  • Nature

    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab221221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-LGR5 antibody [EPR3065Y] (ab75850)

  • Form

    Lyophilised
  • Additional notes

    Reconstitution instructions:

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.

    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.

    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.

    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.

    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • FEX
    • G protein coupled receptor 49
    • G protein coupled receptor 67
    • g protein-coupled receptor fex
    • G-protein coupled receptor 49
    • G-protein coupled receptor 67
    • G-protein coupled receptor HG38
    • GPCR GPR49
    • GPR 49
    • GPR 67
    • GPR49
    • GPR67
    • GRP 49
    • GRP49
    • HG 38
    • HG38
    • Leucine rich repeat containing G protein coupled receptor 5
    • Leucine-rich repeat-containing G-protein coupled receptor 5
    • LGR 5
    • LGR5
    • LGR5_HUMAN
    • MGC117008
    • Orphan G protein coupled receptor HG38
    see all
  • Function

    Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.
  • Tissue specificity

    Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
    Contains 16 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt

References

ab221221 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab221221.
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