Key features and details
- Rabbit polyclonal to LH1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-LH1 antibody
See all LH1 primary antibodies
DescriptionRabbit polyclonal to LH1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
- WB: RT-4, U-251 MG cell lysates and human liver tissue lysate.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityImmunogen affinity purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab262946 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.4 µg/ml.
Use a concentration of 0.4 µg/ml.
FunctionForms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Involvement in diseaseDefects in PLOD1 are the cause of Ehlers-Danlos syndrome type 6 (EDS6) [MIM:225400]. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS6 is characterized by the presence of ocular complications, particularly retinal detachment.
Defects in PLOD1 are the cause of Nevo syndrome (NEVOS) [MIM:601451]. This is a rare, autosomal recessive disorder characterized by increased perinatal length, kyphosis, muscular hypotonia, and joint laxity. Nevo syndrome and EDS-VI have similar clinical phenotypes. Some authors consider that both syndromes are the same clinical entity.
Sequence similaritiesContains 1 Fe2OG dioxygenase domain.
Cellular localizationRough endoplasmic reticulum membrane.
- Information by UniProt
- 2-oxoglutarate 5-dioxygenase 1 antibody
- EDS6 antibody
- LH antibody
Anti-LH1 antibody (ab262946) at 0.4 µg/ml + U-251 MG (formally U-373 MG) (human brain glioma cell line) whole cell lysate
All lanes : Anti-LH1 antibody (ab262946) at 0.4 µg/ml
Lane 1 : RT4 cell lysate
Lane 2 : U-251 MG (formally U-373 MG) (human brain glioma cell line) whole cell lysate
Lane 3 : Human Plasma
Lane 4 : Human liver tissue lysate
Lane 5 : Human tonsil tissue lysate
Western blot staining using ab262946 shows simillar staining to an independent antibody (B)
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab262946 has not yet been referenced specifically in any publications.