Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.0225% Potassium chloride, 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, PBS
Concentration information loading...
PurityProtein G purified
Purification notesAb50790 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum. This antibody was filtered through a 0.22 µm membrane.
Our Abpromise guarantee covers the use of ab50790 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Detects a band of approximately 34 kDa (predicted molecular weight: 43 kDa).|
FunctionMay play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.
Involvement in diseaseDefects in LHX4 are the cause of pituitary hormone deficiency combined type 4 (CPHD4) [MIM:262700]; also known as short stature pituitary and cerebellar defects and small sella turcica. The disorder is characterized by short stature, pituitary and cerebellar defects, and small transverse depression crossing the midline on the superior surface of the body of the sphenoid bone which houses the pituitary gland.
Note=A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1.
Sequence similaritiesContains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
- Information by UniProt
- CPHD4 antibody
- Gsh 4 antibody
- Gsh4 antibody
Anti-Lhx4 antibody [LHX4E11E10] (ab50790) + Immunised recombinant protein.
Predicted band size: 43 kDa
Observed band size: 34 kDa why is the actual band size different from the predicted?
ab50790 has not yet been referenced specifically in any publications.