Recombinant Anti-Lhx8 antibody [EPR5213(2)] (ab137036)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR5213(2)] to Lhx8
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Lhx8 antibody [EPR5213(2)]
See all Lhx8 primary antibodies -
Description
Rabbit monoclonal [EPR5213(2)] to Lhx8 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human fetal brain, Human fetal forebrain and A431 lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR5213(2) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137036 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 39 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 39 kDa. |
Target
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Function
Transcription factor involved in differentiation of certain neurons and mesenchymal cells. -
Sequence similarities
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 431707 Human
- Entrez Gene: 16875 Mouse
- Entrez Gene: 365963 Rat
- Omim: 604425 Human
- SwissProt: Q68G74 Human
- SwissProt: O35652 Mouse
- SwissProt: Q3TMT2 Mouse
- Unigene: 403934 Human
see all -
Alternative names
- Lhx7 antibody
- Lhx8 antibody
- LHX8_HUMAN antibody
see all
Images
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All lanes : Anti-Lhx8 antibody [EPR5213(2)] (ab137036) at 1/1000 dilution
Lane 1 : Human fetal brain lysate
Lane 2 : Human fetal forebrain lysate
Lane 3 : A431 lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP conjugated Goat anti Rabbit IgG at 1/2000 dilution
Predicted band size: 39 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab137036 has been referenced in 5 publications.
- Zhou C et al. FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med 25:3051-3062 (2021). PubMed: 33580754
- Wang JJ et al. Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly. Theranostics 11:4992-5009 (2021). PubMed: 33754040
- Huang D et al. Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration. Stem Cell Res Ther 12:339 (2021). PubMed: 34112263
- Hou L et al. Browning of Pig White Preadipocytes by Co-Overexpressing Pig PGC-1a and Mice UCP1. Cell Physiol Biochem 48:556-568 (2018). PubMed: 30021212
- Zhou C et al. Lhx8 mediated Wnt and TGFß pathways in tooth development and regeneration. Biomaterials 63:35-46 (2015). ChIP, WB . PubMed: 26081866