Overview

  • Product name

    Lidocaine, Voltage gated Nachannel blocker
  • Description

    Voltage gated Na+ channel blocker
  • Biological description

    Voltage gated Na+ channel blocker. Blocks voltage-gated Na+ channels in the inactivated state. Shows local anasthetic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    137-58-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
  • Molecular weight

    234.30
  • Molecular formula

    C14H22N2O
  • PubChem identifier

    3676
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCN(CC)CC(=O)NC1=C(C=CC=C1C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Valverde A Balanced anesthesia and constant-rate infusions in horses. Vet Clin North Am Equine Pract 29:89-122 (2013). Read more (PubMed: 23498047) »
  • Lomax S  et al. Duration of action of a topical anaesthetic formulation for pain management of mulesing in sheep. Aust Vet J 91:160-7 (2013). Read more (PubMed: 23521101) »
  • Liu M & Wood JN The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain. Pain Med 12 Suppl 3:S93-9 (2011). Read more (PubMed: 21752183) »

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