Overview

  • Product name

    Anti-LIGHT/TNFSF14 antibody
    See all LIGHT/TNFSF14 primary antibodies
  • Description

    Rabbit polyclonal to LIGHT/TNFSF14
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human LIGHT/TNFSF14 aa 145-195 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: O43557

  • Positive control

    • Rat brain lysate and kidney lysate; mouse liver tissue.
  • General notes

     This product was previously labelled as LIGHT

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 0.01% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab203578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

When using a fluorescent probe please use dilutions of 1/50 - 1/200.

WB 1/100 - 1/1000. Predicted molecular weight: 26 kDa.
Flow Cyt 1/20 - 1/100.

Target

  • Function

    Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
  • Tissue specificity

    Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Post-translational
    modifications

    N-glycosylated.
    The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
  • Cellular localization

    Cytoplasm; Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 258 antibody
    • CD258 antibody
    • CD258 antigen antibody
    • Delta transmembrane LIGHT antibody
    • Herpes virus entry mediator ligand antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator ligand antibody
    • herpesvirus entry mediator-ligand antibody
    • HVEM L antibody
    • HVEM-L antibody
    • HVEML antibody
    • Ligand for herpesvirus entry mediator antibody
    • LIGHT antibody
    • LTg antibody
    • soluble form antibody
    • TNF14 antibody
    • TNF14_HUMAN antibody
    • TNFSF 14 antibody
    • Tnfsf14 antibody
    • TNFSF14 protein antibody
    • TR 2 antibody
    • TR2 antibody
    • Tumor necrosis factor (ligand) superfamily, member 14 antibody
    • Tumor necrosis factor ligand superfamily member 14 antibody
    • Tumor necrosis factor ligand superfamily, member 14 antibody
    • Tumor necrosis factor receptor like 2 antibody
    • tumor necrosis factor receptor-like 2 antibody
    • Tumor necrosis factor superfamily member 14 antibody
    • Tumor necrosis factor superfamily member LIGHT antibody
    see all

Images

  • All lanes : Anti-LIGHT/TNFSF14 antibody (ab203578) at 1/200 dilution

    Lane 1 : Rat brain lysate
    Lane 2 : Rat kidney lysate

    Secondary
    All lanes : Goat anti-rabbit-HRP at 1/3000 dilution

    Predicted band size: 26 kDa

  • Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded mouse liver tissue sections labeling LIGHT/TNFSF14 with ab203578 at a 1/200 dilution. DAB staining.

References

ab203578 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab203578.
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