Key features and details
- Rabbit polyclonal to LIGHT/TNFSF14
- Suitable for: IHC-P, WB, Flow Cyt
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-LIGHT/TNFSF14 antibody
See all LIGHT/TNFSF14 primary antibodies
DescriptionRabbit polyclonal to LIGHT/TNFSF14
Tested applicationsSuitable for: IHC-P, WB, Flow Cytmore details
Species reactivityReacts with: Mouse, Rat
Predicted to work with: Human
Synthetic peptide within Human LIGHT/TNFSF14 aa 145-195 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: O43557
- Rat brain lysate and kidney lysate; mouse liver tissue.
This product was previously labelled as LIGHT
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 0.01% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203578 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
When using a fluorescent probe please use dilutions of 1/50 - 1/200.
|WB||1/100 - 1/1000. Predicted molecular weight: 26 kDa.|
|Flow Cyt||1/20 - 1/100.|
FunctionCytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Tissue specificityPredominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
Sequence similaritiesBelongs to the tumor necrosis factor family.
The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
Cellular localizationCytoplasm; Secreted and Cell membrane.
- Information by UniProt
- CD 258 antibody
- CD258 antibody
- CD258 antigen antibody
All lanes : Anti-LIGHT/TNFSF14 antibody (ab203578) at 1/200 dilution
Lane 1 : Rat brain lysate
Lane 2 : Rat kidney lysate
All lanes : Goat anti-rabbit-HRP at 1/3000 dilution
Predicted band size: 26 kDa
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded mouse liver tissue sections labeling LIGHT/TNFSF14 with ab203578 at a 1/200 dilution. DAB staining.
ab203578 has not yet been referenced specifically in any publications.