Overview

  • Product name

    Limonin glucoside, Apoptotic agent
  • Description

    Apoptotic agent. Limonin derivative.
  • Biological description

    Apoptotic agent. Limonin (ab141949) derivative. Aromatase inhibitor. Induces mitochondria mediated intrinsic apoptosis. Shows antiproliferative activity. Orally active.
  • Purity

    > 95%
  • CAS Number

    123564-61-4
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    650.67
  • Molecular formula

    C32H42O14
  • PubChem identifier

    56840940
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC(C35C(O5)C(=O)O)(C)C(C6=COC=C6)OC7C(C(C(C(O7)CO)O)O)O)C)C
  • Source

    Citrus sp.

  • Research areas

References

This product has been referenced in:

  • Kim J  et al. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct 4:258-65 (2013). Read more (PubMed: 23117440) »
  • Chidambara Murthy KN  et al. Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis. J Agric Food Chem 59:2314-23 (2011). Read more (PubMed: 21338095) »
  • Perez JL  et al. Limonin methoxylation influences the induction of glutathione S-transferase and quinone reductase. J Agric Food Chem 57:5279-86 (2009). Read more (PubMed: 19480426) »
  • Breksa AP & Manners GD Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside. J Agric Food Chem 54:3827-31 (2006). Read more (PubMed: 16719503) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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