Key features and details
- Rabbit polyclonal to LIMPII
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-LIMPII antibody
See all LIMPII primary antibodies
DescriptionRabbit polyclonal to LIMPII
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
A 16 amino acid synthetic peptide from near the center of Human LIMP2 (AAH21892).
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106519 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.|
FunctionActs as a lysosomal receptor for glucosylceramidase (GBA) targeting.
(Microbial infection) Acts as a receptor for enterovirus 71.
Involvement in diseaseEpilepsy, progressive myoclonic 4, with or without renal failure
Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
Sequence similaritiesBelongs to the CD36 family.
Cellular localizationLysosome membrane.
- Information by UniProt
- 85 kDa lysosomal membrane sialoglycoprotein antibody
- 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2 antibody
- AMRF antibody
Western blot analysis of LIMP2 in mouse liver tissue lysate with LIMP2 antibody at 1 µg/mL in (A) the absence and (B) presence of blocking peptide.
All lanes : Anti-LIMPII antibody (ab106519) at 1 µg/ml
Lane 1 : Human skeletal muscle tissue lysate
Lane 2 : Human skeletal muscle tissue lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 54 kDa
Despite its predicted molecular weight, LIMPII runs at approximately 80 – 85 kDa in SDS-PAGE.
ab106519 has been referenced in 2 publications.
- McNeill A et al. Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. Brain 137:1481-95 (2014). WB ; Human . PubMed: 24574503
- Su PY et al. Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells. BMC Microbiol 12:162 (2012). WB . PubMed: 22853823