Overview

  • Product name

    Anti-LIN54 antibody
  • Description

    Rabbit polyclonal to LIN54
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region between amino acids 50 and 100 of Human LIN54 (NP_919258.2)

  • Positive control

Properties

Applications

Our Abpromise guarantee covers the use of ab138425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function

      Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner.
    • Sequence similarities

      Belongs to the lin-54 family.
      Contains 1 CRC domain.
    • Domain

      The CXC domains mediate DNA-binding.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • CXC domain containing 1 antibody
      • CXC domain-containing protein 1 antibody
      • CXCDC1 antibody
      • JC8.6 antibody
      • Kiaa2037 antibody
      • lin-54 homolog (C. elegans) antibody
      • Lin54 antibody
      • LIN54_HUMAN antibody
      • MIP120 antibody
      • Protein lin-54 homolog antibody
      • protein lin54 homolog antibody
      see all

    Images

    • Detection of LIN54 by immunoprecipitation in HeLa whole cell lysate using ab138425 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). A different antibody against Human LIN54 was used for Western Blot detection step. Chemiluminescence with an exposure time of 3 seconds.

    References

    ab138425 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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