Anti-LIN9/TGS antibody (ab214230)
Key features and details
- Rabbit polyclonal to LIN9/TGS
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-LIN9/TGS antibody
See all LIN9/TGS primary antibodies -
Description
Rabbit polyclonal to LIN9/TGS -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide within Human LIN9/TGS aa 450 to the C-terminus conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q5TKA1-1 -
Positive control
- Human kidney tissue and Mouse bone lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab214230 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/100 - 1/1000. Predicted molecular weight: 62 kDa.
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IHC-P |
1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
1/100 - 1/1000. Predicted molecular weight: 62 kDa. |
IHC-P
1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. -
Tissue specificity
Expressed in thymus and testis. -
Sequence similarities
Belongs to the lin-9 family. -
Cellular localization
Nucleus > nucleoplasm. Found in perinucleolar structures. Associated with chromatin. - Information by UniProt
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Database links
- Entrez Gene: 286826 Human
- Entrez Gene: 72568 Mouse
- Entrez Gene: 689523 Rat
- Omim: 609375 Human
- SwissProt: Q5TKA1 Human
- SwissProt: Q8C735 Mouse
- Unigene: 120817 Human
- Unigene: 275044 Mouse
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Alternative names
- BARA antibody
- Beta subunit-associated regulator of apoptosis antibody
- Beta-subunit associated regulator of apoptosis antibody
see all
Images
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue sections labeling LIN9/TGS using ab214230 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
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Anti-LIN9/TGS antibody (ab214230) at 1/300 dilution + mouse bone lysate
Secondary
Goat anti-rabbit IgG (H+L) HRP conjugated at 1/10000 dilution
Predicted band size: 62 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab214230 has not yet been referenced specifically in any publications.