Overview

  • Product name

    Linoleic acid, PPAR activator.
  • Description

    Essential polyunsaturated fatty acid. PPAR activator.
  • Biological description

    Essential polyunsaturated fatty acid. PPAR activator. Induces apoptosis. Augments cellular oxidant status and induces mitochondrial dysfunction. Modulates the inflammatory process and regulates neutrophil function. Stimulates thromboxanes and prostaglandin production. Shows antithrombotic effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    60-33-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Rao YP & Lokesh BR Modulatory effects of alpha-linolenic acid on generation of reactive oxygen species in elaidic acid enriched peritoneal macrophages in rats. Indian J Exp Biol 52:860-9 (2014). Read more (PubMed: 25241585) »
  • Yang Q  et al. Anti-thrombotic effects of a-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. BMC Complement Altern Med 14:348 (2014). Read more (PubMed: 25252789) »
  • Kelley NS  et al. Conjugated linoleic acid isomers and cancer. J Nutr 137:2599-607 (2007). Read more (PubMed: 18029471) »
  • Soberman RJ  et al. Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. J Biol Chem 260:4508-15 (1985). Read more (PubMed: 3920219) »
  • MOHRHAUER H & HOLMAN RT THE EFFECT OF DOSE LEVEL OF ESSENTIAL FATTY ACIDS UPON FATTY ACID COMPOSITION OF THE RAT LIVER. J Lipid Res 4:151-9 (1963). Read more (PubMed: 14168145) »
  • Bialek A  et al. Enrichment of maternal diet with conjugated linoleic acids influences desaturases activity and fatty acids profile in livers and hepatic microsomes of the offspring with 7,12-dimethylbenz[a]anthracene-induced mammary tumors. Acta Pol Pharm 71:747-61 (0). Read more (PubMed: 25362803) »

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