Anti-LIPA3 antibody - C-terminal (ab180888)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-LIPA3 antibody - C-terminal -
Description
Rabbit polyclonal to LIPA3 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human LIPA3 (C terminal). (17 amino acid peptide; NP_003651).
Database link: O75145 -
Positive control
- 293 cell lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab180888 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 131 kDa (predicted molecular weight: 133 kDa). |
Target
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Function
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. -
Tissue specificity
Expressed only in brain. -
Sequence similarities
Belongs to the liprin family. Liprin-alpha subfamily.
Contains 3 SAM (sterile alpha motif) domains. -
Domain
The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS. -
Cellular localization
Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface. - Information by UniProt
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Database links
- Entrez Gene: 8541 Human
- Entrez Gene: 76787 Mouse
- Entrez Gene: 140591 Rat
- Omim: 603144 Human
- SwissProt: O75145 Human
- SwissProt: P60469 Mouse
- SwissProt: Q91Z79 Rat
- Unigene: 413748 Human
see all -
Alternative names
- LIPA3_HUMAN antibody
- liprin antibody
- Liprin-alpha-3 antibody
see all
Images
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Lane 1 : Anti-LIPA3 antibody - C-terminal (ab180888) at 1 µg/ml
Lane 2 : Anti-LIPA3 antibody - C-terminal (ab180888) at 2 µg/ml
All lanes : 293 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 133 kDa
Observed band size: 131 kDa why is the actual band size different from the predicted?
Protocols
Datasheets and documents
References
ab180888 has not yet been referenced specifically in any publications.