Anti-LIPA3 antibody - C-terminal (ab180888)

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Overview

  • Product name

    Anti-LIPA3 antibody - C-terminal

  • Description

    Rabbit polyclonal to LIPA3 - C-terminal

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide corresponding to Human LIPA3 (C terminal). (17 amino acid peptide; NP_003651).
    Database link: O75145

  • Positive control

    • 293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab180888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 131 kDa (predicted molecular weight: 133 kDa).

Target

  • Function

    May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.

  • Tissue specificity

    Expressed only in brain.

  • Sequence similarities

    Belongs to the liprin family. Liprin-alpha subfamily.
    Contains 3 SAM (sterile alpha motif) domains.

  • Domain

    The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.

  • Cellular localization

    Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • LIPA3_HUMAN antibody
    • liprin antibody
    • Liprin-alpha-3 antibody
    • LPNA3 antibody
    • Ppfia3 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3 antibody
    • protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 antibody
    • protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3 antibody
    • PTPRF-interacting protein alpha-3 antibody
    see all

Images

  • Western blot - Anti-LIPA3 antibody - C-terminal (ab180888)
    Western blot - Anti-LIPA3 antibody - C-terminal (ab180888)
    Lane 1 : Anti-LIPA3 antibody - C-terminal (ab180888) at 1 µg/ml
    Lane 2 : Anti-LIPA3 antibody - C-terminal (ab180888) at 2 µg/ml

    All lanes : 293 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 133 kDa
    Observed band size: 131 kDa
    why is the actual band size different from the predicted?

References

ab180888 has not yet been referenced specifically in any publications.

Publishing research using ab180888? Please let us know so that we can cite the reference in this datasheet.

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