Anti-LIPA3 antibody - C-terminal (ab180888)

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Overview

  • Product name
    Anti-LIPA3 antibody - C-terminal
    See all LIPA3 primary antibodies
  • Description
    Rabbit polyclonal to LIPA3 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human LIPA3 (C terminal). (17 amino acid peptide; NP_003651).
    Database link: O75145

  • Positive control
    • 293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab180888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 131 kDa (predicted molecular weight: 133 kDa).

Target

  • Function
    May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
  • Tissue specificity
    Expressed only in brain.
  • Sequence similarities
    Belongs to the liprin family. Liprin-alpha subfamily.
    Contains 3 SAM (sterile alpha motif) domains.
  • Domain
    The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
  • Cellular localization
    Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • LIPA3_HUMAN antibody
    • liprin antibody
    • Liprin-alpha-3 antibody
    • LPNA3 antibody
    • Ppfia3 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3 antibody
    • protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 antibody
    • protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3 antibody
    • PTPRF-interacting protein alpha-3 antibody
    see all

Images

  • Western blot - Anti-LIPA3 antibody - C-terminal (ab180888)
    Western blot - Anti-LIPA3 antibody - C-terminal (ab180888)
    Lane 1 : Anti-LIPA3 antibody - C-terminal (ab180888) at 1 µg/ml
    Lane 2 : Anti-LIPA3 antibody - C-terminal (ab180888) at 2 µg/ml

    All lanes : 293 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 133 kDa
    Observed band size: 131 kDa (why is the actual band size different from the predicted?)

References

ab180888 has not yet been referenced specifically in any publications.

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