Overview

  • Product name
    Anti-LIPT2 antibody - N-terminal
    See all LIPT2 primary antibodies
  • Description
    Rabbit polyclonal to LIPT2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LIPT2 aa 12-43 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: A6NK58

  • Positive control
    • MCF-7 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab173981 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab173981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 25 kDa.

Target

  • Function
    Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  • Pathway
    Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.
  • Sequence similarities
    Belongs to the lipB family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 2.3.1.181 antibody
    • FCT2 antibody
    • Lipoate-protein ligase B antibody
    • Lipoyl(octanoyl) transferase 2 (putative) antibody
    • Lipoyl/octanoyl transferase antibody
    • Lipt2 antibody
    • LIPT2_HUMAN antibody
    • mitochondrial antibody
    • Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase antibody
    • OTTHUMP00000230589 antibody
    • OTTHUMP00000230590 antibody
    • OTTHUMP00000230591 antibody
    • Putative lipoyltransferase 2 antibody
    • Putative lipoyltransferase 2, mitochondrial antibody
    • Putative octanoyltransferase, mitochondrial antibody
    • SLC22A16 antibody
    see all

Images

  • Anti-LIPT2 antibody - N-terminal (ab173981) at 1/100 dilution + MCF-7 cell line lysates at 35 µg

    Predicted band size: 25 kDa

References

This product has been referenced in:
  • Habarou F  et al. Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy. Am J Hum Genet 101:283-290 (2017). WB ; Human . Read more (PubMed: 28757203) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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