Key features and details
- GSK3β inhibitor
- CAS Number: 7447-41-8
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameLithium chloride, GSK3beta inhibitor
Direct, non-competitive GSK3β inhibitor in vitro (Ki = 2 mM). Elicits various neuropharmacological effects.
Chemical nameLithium chloride
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120853 has been referenced in 3 publications.
- Wang Y et al. Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/ß-Catenin Axis. Drug Des Devel Ther 15:245-257 (2021). PubMed: 33519190
- Singh VP et al. Enhanced Generation of Induced Cardiomyocytes Using a Small-Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming. J Am Heart Assoc 9:e015686 (2020). PubMed: 32500803
- Monaco SA et al. Lithium Inhibits GSK3ß and Augments GluN2A Receptor Expression in the Prefrontal Cortex. Front Cell Neurosci 12:16 (2018). PubMed: 29449801