Key features and details
- Mouse monoclonal [ARG1/1125] to Liver Arginase
- Suitable for: Protein Array, IHC-P, WB
- Reacts with: Human
- Isotype: IgG3
Product nameAnti-Liver Arginase antibody [ARG1/1125]
See all Liver Arginase primary antibodies
DescriptionMouse monoclonal [ARG1/1125] to Liver Arginase
Tested applicationsSuitable for: Protein Array, IHC-P, WBmore details
Species reactivityReacts with: Human
Recombinant fragment within Human Liver Arginase aa 1-150. The exact sequence is proprietary. 87 amino acids long. NCBI Accession No. 440934.
Database link: P05089
- Human hepatocellular carcinoma tissue. 293T cells. Huma liver lysate. Recombinant Human Liver Arginase protein fragment.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 0.05% BSA, 99% PBS
Concentration information loading...
PurityProtein A/G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab215843 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Protein Array||Use at an assay dependent concentration.|
|IHC-P||Use a concentration of 2 - 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 35 kDa.|
PathwayNitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
Involvement in diseaseDefects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
Sequence similaritiesBelongs to the arginase family.
- Information by UniProt
- A I antibody
- Al antibody
- ARG 1 antibody
ab215843 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
All lanes : Anti-Liver Arginase antibody [ARG1/1125] (ab215843) at 1 µg/ml
Lane 1 : recombinant Human Liver Arginase protein fragment
Lane 2 : Human liver lysate
Predicted band size: 35 kDa
Immunohistochemical analysis of formalix-fixed paraffin-embedded Human hepatocellular carcinoma tissue, labeling Liver Arginase using ab215843 at 4 µg/mL.
ab215843 has not yet been referenced specifically in any publications.